Oesophageal cancer is one of the deadliest cancers, with patients having little chance of survival following initial diagnosis. A key challenge for the early detection of oesophageal cancer is the absence of low cost, non-invasive (or minimally invasive) tools that can detect early pre-cancerous or cancerous changes in the oesophagus.
Breath analytics is a powerful, cutting edge technology that can be used to non-invasively, rapidly and with high sensitivity and specificity detect pre-cancerous and cancerous lesions.
Dr Yazbek is leading a research team that has built a unique capability in Australia, to identify and validate clinically relevant breath markers of oesophageal cancer that can be translated into point of care devices, to aid in the rapid, non-invasive assessment of patients at high risk of developing oesophageal cancer
What we aim to achieve
A simple, painless, rapid, non-invasive breath test will not only encourage more people to have their oesophageal health checked on a more regular basis, it will also lead to earlier diagnosis, leading to a better chance of cancer eradication and patient survival. These tests can be done in the doctor’s clinic, the patient’s home, or even mailed out to rural and remote communities, expanding the reach of modern health care.
Our next steps and milestones
Cancer Council SA's funding has provided the foundation required to make our initial breakthroughs. We now hope to test our exciting breath tests in patients, to validate their clinical application, leading to the development of a clinical tool that could change clinical management of oesophageal cancer patients.
What motivates me
The opportunity to change the world for good, and improve the health of millions world-wide is what drives and motivates me to pursue my research into cancer.
My message to supporters
Medical research is challenging but the rewards are countless. The best medical research is done in environments founded on secured and continuous funding. We depend on your generosity to ensure our discoveries progress from the laboratory to the clinic, to make real differences for cancer patients.