Most people with pancreatic cancer do not have a family history of the disease. However about one in ten people who develop pancreatic cancer have an inherited faulty gene that increased their risk. Some inherited syndromes that may cause pancreatic cancer include:
- Peutz-Jeghers syndrome, a type of colonic polyp syndrome
- the familial breast cancer genes (BRCA1and BRCA2)
- familial atypical multiple mole melanoma syndrome
- Lynch syndrome – or hereditary nonpolyposis colorectal cancer (HNPCC)
- hereditary pancreatitis.
Some Pancreatic Neuroendocrine Tumours (PNETs) are caused by a rare inherited syndrome, such as multiple endocrine neoplasia type 1 (MEN-1) or neurofibromatosis.
If you are concerned about your family history or if you want to know more about genetic testing, talk to your doctor.
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